ABSTRACT

The incidence of pregnancies with three or more fetuses has increased markedly over the past two decades. The change has been attributed to the introduction and widespread use of new techniques for ovulation induction and the replacement of multiple embryos during in vitro fertilization-embryo transfer (IVF-ET).1-3 These techniques have been a matter of concern, since triplet and higher order multiple pregnancies have long been associated with an increased risk of maternal complications, and a high prevalence of perinatal and neonatal morbidity and mortality.48 Simultaneously, the developing experience with multifetal pregnancy reduction offers a new option for the management of such pregnancies. There is therefore a need to evaluate the management and outcome of high order multiple pregnancies.