Role of Cadmium in the Etiology of Cancer of the Prostate
Exposure to cadmium, a very toxic metal, continues to be a substantial envi ronmental and occupational concern. Cadmium has several diverse acute and chronic toxic effects (29,30), including carcinogenicity (47,98,101). Cadmium was recently accepted by the International Agency for Research on Cancer as a human carcinogen (47), primarily based on activity as a pulmonary carcinogen (82). Cadmium is also an effective and potent rodent carcinogen and has been as sociated with tumors of the lung, testes, and hematopoietic system among other possible sites (47,96,98,101).