ABSTRACT
I. INTRODUCTION The great potential of gene therapy has recently been supported by successful treatments of immune deficiency and cancer patients (1,2). However, much remains to be solved before gene therapy becomes a standard procedure. One major obstacle is the low efficiency of gene transfer (3); thus, further development of vectors is necessary. In this context, baculoviruses have raised increasing interest because they have a long history as safe and efficient gene delivery tools in insect cells (4), and the long-lived dogma of incompability with mammalian cells has recently been revised (5-7).
