ABSTRACT

This landmark volume discusses the characteristics and impact of the remodeling process on airway function and clinical disease expression within the airway in asthma, covering pharmacological therapies and possible future targets relevant to regulating the remodeling process.

Emphasizes the importance of treating underlying airway inflammat

chapter 1|4 pages

What Does Airway Remodeling Mean? Its Relevance to Asthma

JEAN BOUSQUET ANTONIO MAURIZIO VIGNOLA INSERM U454 Palermo, Italy Villeneuve

chapter 2|22 pages

How Can We Assess Airway Remodeling Using Imaging?

DANY JAFFUEL JEAN BOUSQUET Montpellier University and Service des Mala dies Respiratoires- Villeneuve INSERM U454 Villeneuve FABRICE JEAN PAGANIN n, France

chapter 4|12 pages

Physiological Consequences of Lung Remodeling in Asthma

BJORN JONSON Lund I. Introduction

chapter 5|22 pages

Consequences of Airway Remodeling to the Patient

Helsinki University and ity Central Hospital I. Introduction

chapter 7|24 pages

The Bronchial Vessels in Airway Remodeling

JOHN W. WILSON and XUN LI The Alfred Campus I. Introduction

chapter 8|10 pages

The Extracellular Matrix of the Airways and Bronchial Asthma

WILLIAM R. ROCHE l Hospital Southampton, England

chapter 9|20 pages

Role of the Airway Nervous System in Airway Remodeling

TONY R. BAI DARRYL A. KNIGHT lumbia U tralia Vancouver, British Columbia, Canada I. Introduction

chapter 10|22 pages

The Influence of Pharmacological Therapy on Airway Remodeling in Asthma

PETER H. HOWARTH Hospital I. Introduction

chapter 11|12 pages

The Human Eosinophil and Its Role in Airway Remodeling

PER VENGE sala I. Introduction

chapter 13|28 pages

Airway Smooth Muscle as a Target for Novel Antiasthma Drugs Acting on Airway Wall Remodeling

ALASTAIR G. STEWART University of Melbourne Parkville, Victoria, Australia

chapter 14|16 pages

Growth Factor-Extracellular Matrix Interactions in Bronchial Tissue in Asthma

JANIS K. SHUTE Hospital I. Introduction

chapter 15|10 pages

Is There an Animal Model of Airway Remodeling? A . Pauwels

JOHAN C. KIPS and ELS PALMANS and ROMAIN A. PAUWELS NELE VANACKER ity Hospital Ghent, Belgium I. Introduction

chapter 16|20 pages

Future Directions in Airway Remodeling

Hospital Prahran, Australia