ABSTRACT

Wet granulation is a subset of size enlargement (1-5), which involves any process whereby small particles are agglomerated, compacted, or otherwise brought together into larger, relatively permanent structures in which the original particles can still be distinguished. Granulation technology and size-enlargement processes have been used by a wide range of industries, from the pharmaceutical industry to fertilizer or detergent production to the mineral processing industries. Size enlargement generally encompasses a variety of unit operations or processing techniques dedicated to particle agglomeration. These processes can be loosely broken down into agitation and compression methods.