chapter  19
12 Pages

Depression and Dementia

ByEugene H. Rubin

Depressive disorders are common and are among the most disabling medical illnesses (1-3). The

morbidity and mortality associated with major medical disorders are substantially increased when a

depressive disorder co-occurs (3-6). Dementias are another group of central nervous system

disorders that are devastating and disabling. Depression occurring in the presence of dementia leads

to increased disability, suffering, and mortality (7,8). In this chapter, general issues concerning

depressive disorders will be reviewed, followed by a discussion of the interactions and influences of

depression on dementia of the Alzheimer’s type (DAT). The final section will deal with treatment