ABSTRACT
In 1994 two key publications summarized the knowledge on the state of the art of stratum
corneum biology and dry skin, namely: “Stratum corneum moisturization at the molecular
level” (1) and “The correlation of water content with ultrastructure in the stratum
corneum.” Since then, significant advances have been made in our understanding of the
pathophysiology of dry skin. This chapter will review these recent findings and from these
propose a new model of a dry skin cycle (Fig. 1).
