ABSTRACT
INTRODUCTION Liposomes represent one of the fi rst “nanoscale” technologies used in drug delivery, and continue to be a source of innovative solutions because of the vast variety of lipid compositions, size, charge, and other characteristics that can be tailored to a given delivery problem. In addition, the relatively nontoxic nature of many liposomal compositions has been well established. With the recently renewed importance of delivery vehicles for biopharmaceutical therapeutics with intracellular targets such as siRNA, liposomes continue to be an attractive nontoxic formulation choice that can function well in many situations.
