ABSTRACT

In this section the term PUVA therapy will refer to oral methoxsalen photochemotherapy in which a patient ingests methoxsalen and is subsequently exposed to an indoor artificial source of ultraviolet A (UVA) (320400 nm) radiation (1-3). This therapy has been used for treating moderate to severe psoriasis for nearly three decades. During this time it has undergone intense scrutiny, and its benefits and risks have been clearly defined. Successful use of PUVA therapy requires a well-informed physician, a trained staff, and an educated, motivated patient. While this can be said of all psoriasis treatment, it is particularly true for PUVA therapy because of the complexity of the regimen.