chapter  1
67 Pages

Early Symptomatic Breast Cancer

A 65-year-old woman presented with a fourweek history of a lump in the superior aspect of the right breast that was slightly tender to palpation but not associated with any nipple discharge. The patient had no previous breast problems and had undergone regular screening mammography until the age of 64 years (never recalled). Several family members had been affected with breast cancer including the patient’s sister who developed the disease at the age of 47 years. In addition, both maternal and paternal grandmothers had developed pre-and postmenopausal breast cancer, respectively together with a maternal aunt (postmenopausal disease). The patient had two children both of whom were breast-fed (age at birth of eldest child 22 years). She previously had a hysterectomy with ovarian preservation and had used hormone replacement therapy for a duration of two years in total.