ABSTRACT
Diarrheal diseases remain a leading global health problem. It has been estimated that (3-5)×109 episodes of diarrhea, resulting in approximately 4 million deaths, occur annually in developing countries with the highest incidence and severity in children below the age of 5 years [1,2]. About half of these diarrheas are caused by bacteria that produce one or more enterotoxins. Cholera, resulting from infection with Vibrio cholerae bacteria, is the most severe of these “enterotoxic enteropathies,” while infection with enterotoxigenic Escherichia coli (ETEC) is causing the largest number of cases [3,4].
