ABSTRACT

Alzheimer’s disease (AD) is a progressive neurological disorder that imposes an enormous burden on society [1]. Unlike some other progressive neurological diseases, such as subacute sclerosing panencephalitis, progressive multifocal leukoencephalopathy, and Creutzfeldt-Jakob disease, there is no evidence to suggest that AD is the result of an infection. Hence it is all the more remarkable that AD may be the first of the chronic degenerative neurological diseases to be amenable to specific intervention through therapeutic and preventative immunization.