chapter  3
6 Pages

Time Lapse, the Cell Cycle, Distribution of Morphokinetic Timings, and Known Implantation Data

ByAlison Campbell

A cell cycle is a series of complex events involving cellular and nuclear processes through particular phases that ensure the cell’s division into two daughter cells. Mitosis consists of nuclear division and cytokinesis and consists of several phases: prophase, prometaphase, metaphase, anaphase, and telophase. These are preceded by interphase which encompasses stages GAP-1 (G1), Synthesis (S), and GAP-2 (G2) of what is known as the cell cycle. The duration of cell cycles in the human preimplantation embryo appears to be related to embryo viability.1 Prolonged or rapid cell cycles could be associated with DNA repair, cellular rearrangements, or failure of an embryo to undergo cell cycle checkpoints. Both cycles could potentially compromise embryo development.2