chapter  1
32 Pages

Overview and Recent Advances in QSAR Studies

ByRahul P. Gangwal, Mangesh V. Damre, Abhay T. Sangamwar

Abstract .....................................................................................................................2 1.1 Introduction .....................................................................................................2 1.2 History of QSAR Development ......................................................................3 1.3 QSAR Methodologies ......................................................................................6 1.4 Fragment-Based 2D-QSAR ............................................................................6 1.5 3D-QSAR .......................................................................................................10 1.6 Multidimensional (4D-6D) QSAR Methods ................................................13 1.7 Feature or Descriptor Selection .....................................................................13 1.8 Statistical Methods for Generation of QSAR/QSPR Model ..........................18 1.9 Conclusions ....................................................................................................28 Keywords ................................................................................................................28 References ...............................................................................................................28