The Food Quality Protection Act and the Safe Drinking Water Act
Pesticides are widely used in the United States, particularly in agriculture. Over the last four decades, public controversy has swirled around the government’s regulatory programs, usually in connection with speciﬁc pesticides such as dichloro diphenyl trichloroethane (DDT) in the 1960s; Alar1, the plant growth regulator used on apples featured on the CBS newsmagazine ‘‘60 Minutes’’ in the 1980s; and the genetically modiﬁed variety of corn, StarLink1, that was illegally introduced into the human food supply. As a consequence, government agencies responsible for regulatingpesticideshavehad todealwith abroadarray of cutting-edge scientiﬁc issues.These issues range fromsetting the government’s policies on cancer risk assessment to pioneering work in the ﬁeld of ecological risk assessment, to deﬁning for the country and for the world how to evaluate the safety of the products of modern biotechnology. This chapter focuses
on the latest addition to this long history of scientiﬁc accomplishments-the validation of newassays for evaluating the effects of substanceson the endocrine system and the U.S. Environmental Protection Agency’s (EPA) pioneering efforts to improve chemical risk assessment methodology.