A wide variety of drugs are used to treat abnormal uterine bleeding. Medical therapy is indicated when there is no obvious pelvic abnormality and the woman wishes to retain her fertility. Whereas the number of hysterectomies for menorrhagia has been estimated to have fallen by 36% between 1989 and 2002/3, and the number of endometrial ablations is increasing, some women do not wish to have surgery. 1,2 Medical treatment avoids surgery, but may have side effects and must be taken long term. 3 Thus, the drug regimen chosen must be effective, have few or mild side effects, and must be acceptable to the patient.