chapter  30
10 Pages

Cardiovascular Computed Tomography: A Research Perspective

ByYue Dong, Erik L Ritman

Continued developments in CT imaging are in part driven

by the quest for increased accuracy, sensitivity and speci-

ficity of the measurements made from those CT images.

These can be achieved by ‘brute force’ improvement of

the current CT scanner capabilities by technological

advances applied to the systems. This approach is usually

limited by the cost and technological possibilities. However,

some plausible capabilities (which often cannot be fully eval-

uated as to their value until a system is made available),

which are suggested from new insights obtained from

research or clinical experience may only be achievable by use

of aspects of x-ray interaction with matter different from the

current use of attenuation of x-rays. All these potential

developments must keep in mind the radiation exposure

associated with a CT scan that has to be balanced against the

possible harm done to a subject if the CT scan is not

performed. Thus, for a person aged 65, repeated CT scans

for monitoring of progression of coronary artery disease

may be more readily justified than CT-based screening of