ABSTRACT

The importance of developing new effective methodologies for enantioselective synthesis is becoming manifestly evident. An increasing number of pharmaceutical, flavor and fragrance, and agrochemical products rely on the availability of enantiomerically pure intermediates that can serve as building blocks for further structural and/or stereochemical elaboration. Of the various techniques known for the preparation of specific optical isomers, asymmetric catalysis is emerging as one of the most efficient, versatile, and cost-effective methods for the preparation of a wide range of enantiomerically enriched compounds.