ABSTRACT
Cystic brosis (CF) is an autosomal recessive disease with multisystem involvement, and with particularly devastating respiratory impact. e respiratory tract can be considered to extend from the lips and nostrils to the alveoli, being divided into an upper airway and a lower airway at the level of the larynx, and is lined throughout with respiratory pseudostratied ciliated epithelium. Although the dominant features relate to lower respiratory tract infections and pancreatic insuciency, the upper airway sites most signicantly aected by the disease are the nose and paranasal sinuses.
