ABSTRACT

The management of recurrent miscarriage (RM) is a clinical challenge considering that in the majority of the couples no evidence based treatment is available to increase live birth rates or decrease miscarriage rates. Unexplained pregnancy loss is a diagnosis of exclusion, and is used when no aetiological factor is found on routine investigation.1 It is not a definitive diagnosis. Although there is no effective therapy for unexplained pregnancy loss, the condition is so distressing for the affected couple and frustrating for the clinician that nonevidence based diagnoses and treatment are often proposed rather than adhering to guidelines that state that treatment for these couples may not be indicated.2