chapter  9
10 Pages

TRANSPORT OF MEDICINAL SUBSTANCES BY CHITOSAN FILMS

ByA. S. Shurshina, E. I. Kulish, V. V. Chernova, V. P. Zaharov

Abstract ................................................................................................... 94 9.1 Introduction .................................................................................... 94 9.2 Experimental Part .......................................................................... 94 9.3 Results and Discussion .................................................................. 95 Keywords .............................................................................................. 100 References ............................................................................................. 100

ABSTRACT

Sorption and diffusive properties of films are studied. Kinetic curves of release of medicinal substances, having abnormal character are shown. The analysis of the obtained data showed that a reason for rejection of regularities of process of transport of medicinal substance from chitosan films from the classical fikovsky mechanism are structural changes in a polymer matrix, including owing to its chemical modification at interaction with medicinal substance.