chapter  20
Dermal Decontamination and Percutaneous Absorption
ByRonald C. Wester, Howard I. Maibach
Pages 14

Although decontamination of a chemical from the skin is commonly done by washing with soap and water, as it has been assumed that washing will remove the chemical, recent evidence suggests that often the skin and the body are unknowingly subjected to enhanced penetration and systemic absorption/toxicity because the decontamination procedure does not work or may actually enhance absorption. This chapter reviews some of the recent literature, then offers new in vitro and in vivo techniques to determine skin decontamination.