chapter  27
26 Pages

Mechanisms and Therapeutic Applications of Immune Modulatory Oligodeoxynucleotide and Oligoribonucleotide Ligands for Toll-Like Receptors

WithJörg Vollmer, Arthur M. Krieg

Most of the therapeutic applications for synthetic oligodeoxynucleotides (ODN) and oligoribonucleotides (ORN) relate to the role of DNA as the genetic blueprint, and to mechanisms of manipulating gene expression based on Watson-Crick base pairing to endogenous nucleic acids.