ABSTRACT
It is perhaps not surprising that water molecules are strongly affected by their surroundings. Water properties near interfaces differ signicantly from the bulk, given that interactions with interface components affect the structural features associated with the hydrogen bond network and impact molecular mobility. Further restrictions on mobility arise because of connement: In various selfassembled structures, such as folded proteins, vesicles, and reverse micelles, water droplets are conned to a nanoscopic volume over periods that are long on the molecular scale. For many practical purposes then, the overall scale of molecular motion is bounded by the size and shape of the conning region.
