During the past decades, nanostructured materials have been widely investigated for a huge spectrum of advanced technological applications, ranging from microelectronics to solar cells (Narayan 2012; Ferric et al. 2013; Kujawa and Winnik 2013). In recent years, multifunctional nanoparticle systems have been developed owning specic features that render them particularly suitable in biomedicine, for applications like medical diagnosis, drug delivery, and prosthetics (Gao and Xu 2009). Indeed, the exploitation of nanotechnology tools toward the development of biomedical devices has been found to allow for the control of the interactions between material surfaces and biological entities down to the molecular level. In this way, nanosurfaces, nanostructures, and, more generally, nanomaterials have been used in order to mimic the biological microenvironment and thus to promote specic cellular functions, like adhesion, mobility, and dierentiation (Ferreira 2009).