Handbook of Drug Screening
DOI link for Handbook of Drug Screening
Handbook of Drug Screening book
Handbook of Drug Screening
DOI link for Handbook of Drug Screening
Handbook of Drug Screening book
Edited ByRamakrishna Seethala, Prabhavathi Fernandes
Edition 1st Edition
First Published 2001
eBook Published 24 July 2001
Pub. location Boca Raton
Imprint CRC Press
Pages 520 pages
eBook ISBN 9780429208201
SubjectsBioscience
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Seethala, R. (Ed.), Fernandes, P. (Ed.). (2001). Handbook of Drug Screening. Boca Raton: CRC Press, https://doi.org/10.1201/9780203908570
A presentation of screening techniques, modern technologies, and high-capacity instrumentation for increased productivity in the development and discovery of new drugs, chemical compounds, and targeted delivery of pharmaceuticals. It contains practical applications and examples of strategies in cell-based and cell-free screens as well as homogeneou
TABLE OF CONTENTS
chapter 1|4 pages
Moving Into the Third Millennium After a Century of Screening
ByPrabhavathi B. Fernandes
chapter 2|26 pages
Basic Considerations in Designing High-Throughput Screening Assays
ByAssays Duane Bronson, Nathaniel Hentz, William P. Janzen, Mark D. Lister, Karl Menke, Jeffrey Wegrzyn, G. Sitta Sittampalam
chapter 4|60 pages
Homogeneous Assays for High-Throughput and Ultrahigh- Throughput Screening
ByRamakrishna Seethala
chapter 6|36 pages
Molecular Genetic Screen Design for Agricultural and Pharmaceutical Product Discovery
ByDonald R. Kirsch, William Baumbach, Julia N. Heinrich, Margaret Lai, Mark H. Pausch, Laura Sarokin, Sanford Silverman, James C. Walsh
chapter 7|76 pages
Receptor Screens for Small Molecule Agonist and Antagonist Discovery
ByRamakrishna Seethala
chapter 8|18 pages
Functional Assay Screens
ByMaria L. Webb, Robert A. Horlick, Bassam Damaj, Kirk McMillan
chapter 11|22 pages
High-Throughput Screening Assays for Detection of Transcription
ByMohanram Sivaraja
chapter 12|26 pages
Screening of Combinatorial Biology Libraries for Natural Products Discovery
ByChristopher J. Silva, Paul Brian, Todd Peterson
chapter 13|20 pages
Higher-Throughput Screening Assays With Human Hepatocytes for Hepatotoxicity, Metabolic Stability, and Drug–Drug Interaction Potential
ByAlbert P. Li
chapter 14|12 pages
High-Throughput Screening for Metabolism-Based Drug–Drug Interactions
ByVaughn P. Miller, Charles L. Crespi
chapter 16|14 pages
Genomics/Functional Proteomics for Identification of New Targets
ByA. Donny Strosberg
chapter 17|30 pages
Bioinformatics: Identification of Novel Targets and Their Characterization
ByChandra S. Ramanathan
chapter 20|38 pages
Assay Miniaturization: Developing Technologies and Assay Formats
ByKevin R. Oldenburg, Ilona Kariv, Ji-hu Zhang, Thomas D. Y. Chung, and Siqi Lin
chapter 21|20 pages
Screening in the NanoWorld: Single-Molecule Spectroscopy and Miniaturized High-Throughput Screening
ByRodney Turner, Dirk Ullmann, Sylvia Sterrer
