Twin-Screw Extrusion and Screw Design
For those unacquainted with twin-screw extruders (TSEs) there is cause for
cautious optimism in knowing that the use of this well proven and versatile
tool is within grasp to make a better, more repeatable, ‘‘good-manufacturing-
practice’’ (GMP) product. However, given the peculiar nature of pharmaceut-
ical-grade materials and processes, potential users should also exercise caution
about importing solutions that worked for plastics and rubber, which served as
the preamble for most of this work.