ABSTRACT

A recent analysis of pooled data from ECST and NASCET showed that benefit from CEA is decreased in women, partly to a higher operative risk than in men (22). A recent systematic review of all publications reporting data on the association between sex and perioperative risk of stroke and/or death following CEA from 1980 to 2003 showed that the higher operative risk in women is also seen in routine clinical practice (23). Among 21 studies that reported data on sex and perioperative risk, the rate of operative stroke and death was nearly 50% higher in women than in men (1.45, 95% CI¼ 1.2-1.6, P< 0.001).