chapter  10
17 Pages

Quantification of MS lesion evolution in a serial MRI study

Serial magnetic resonance imaging (MRI) of patients has become increasingly attractive due to the non-invasive image acquisition, the shorter scanning and therefore decreased patient time, and the high spatial and tissue resolution. Time series scans reveal information about significant changes in diseased anatomical regions, about the effects of a drug or radiotherapy treatment, or about subtle morphological changes caused by neurological disease. The temporal sampling provides information about both morphological and functional changes.