chapter  13
8 Pages

Inter-Ethnic Differences in the Susceptibility to Drug- Induced QT Interval Prolongation and Torsade de Pointes

BySatish Singh

The title of my subject is Inter-Ethnic Differences in The Susceptibility to Drug-Induced QT Interval Prolongation and Torsade de Pointes. What I am going to speak about is a drug called teradaline, which was licensed in the United Kingdom in July 1986 and subsequently withdrawn worldwide in September 1991 because of 69 cases of torsade de pointes that were reported very quickly over a period of just 18 months. I make no apology for selecting this subject because the number of cardiac drugs that have gone by the wayside because of their arrhythmic effect and the number of noncardiac drugs that have similarly gone by the wayside makes this an important subject.