ABSTRACT
Methylation is a vital biochemical reaction that supports the neurological, cardiovascular, hormone, immune and detoxication systems, DNA/RNA structure and function and other key metabolic systems.1 ere are many nutrients that support this biochemical process, including methylcobalamin (also known as methyl-B12 [MB-12]), dimethylglycine, and trimethylglycine (TMG).
l-methyl-folate (the active form of folic acid) is important in supporting the methylation pathway as well, and is one of the nutrients that is oen needed to maintain the proper balance of nutritional support at the cellular level. ere are two key biochemical pathways related to methylation that need to be discussed. e balance between these processes is critical in order to maintain the normal balance of cofactors related to brain health. ese two pathways are called methylation (also known as re-methylation) and transsulfuration.
