ABSTRACT
In this chapter, the authors review structural and functional aspects that regulate cyclic adenosine monophosphate (AMP) formation by the enzyme adenylyl cyclase and how cyclic AMP generated as a consequence of hormonal stimulation of adenylyl cyclase regulates the cellular response. They also review the state of their knowledge on the regulation of the adenylyl cyclase, cyclic AMP-dependent protein kinase enzyme systems by Lutropin (LH). The message carried by LH is transmitted via its binding to the membrane receptor through the plasma membrane to the interior of the cell by the stimulation of the adenylyl cyclase enzyme complex. The understanding of the mechanism by which occupied hormone receptors stimulate cyclic AMP formation by the enzyme adenylyl cyclase requires a prior understanding of both structural and functional properties of this response system. All of the intracellular actions attributed to cyclic AMP are generally believed to be mediated by cyclic AMP-dependent protein kinases.
