ABSTRACT

In the present study, medicinal plant Biophytum sensitivum was used to evaluate the hypoglycaemic activity against alloxan-induced diabetic albino rat model. Elevated levels of blood glucose, HbA1C, and glycogen and decreased levels of insulin were observed in alloxan-induced diabetic rats. Treatment with different extracts of B. sensitivum and glibenclamide significantly increased the blood glucose, HbA1C, and liver glycogen levels. Among the extracts, ethanol extracts of B. sensitivum recovered the diabetic condition. Thus, it is concluded that the herbal plant B. sensitivum used for the treatment of hyperglycemia and also considered as the promising drug candidate for the treatment of hyperglycaemic conditions.