ABSTRACT

Self-assembly is a process in which molecules assemble themselves to form an organized stable structure. Various efforts for the development of new techniques based on the self-assembly of small bioactive and biocompatible molecules are showing huge opportunity in the field of molecular design bearing a broad range of applications. The self-assembly of peptide molecules is driven by several noncovalent interactions. Cyclic peptides are those in which the polypeptide chain is connected through a circular sequence of bonds. Peptide-based materials have great potential for use as drug delivery systems. Peptides self-assemble to form nanovesicles, which have considerable applications in drug delivery. The demand for self-assembling peptides is increasing in the field of regenerative medicine. The emergence of the field of bioactive peptides is gaining massive importance due to their various antimicrobial activities. Antimicrobial peptides also named as host defense peptides target and kill Gram-positive and Gram-negative bacteria, enveloped viruses, fungi, and even cancerous cells.