ABSTRACT
Recurrent pregnancy loss (RPL) is one of the most challenging conditions in reproductive medicine for patients and physicians alike. M. Cozzolino et al. performed a retrospective cohort study investigating adverse pregnancy outcomes in women with RPL compared to a control group of couples attending a low-risk antenatal unit. N. Hughes et al. examined the obstetric outcome in 88 women with a past history of three or more consecutive pregnancy losses and compared the results to a control group drawn from their local obstetric population. An additional putative mechanism linking preeclampsia and recurrent pregnancy loss is obesity. Obesity has been associated with both recurrent pregnancy loss and preeclampsia. Patients with RPL seem to be at increased risk for developing several complications of pregnancy. Two more studies have supported the association between preterm birth and recurrent pregnancy loss by demonstrating a “dose-dependent effect.”
