This chapter aims to analyze the complex dynamics of economic regionalism in Latin America and its interconnection with the events in the Pacific Rim. To achieve this objective, the chapter is divided into three sections. An evaluation of the current state of Latin America regionalism is presented in the first section. The second section examines the proliferation of regionalism, transregionalism and cross-regionalism in Asia-Pacific, as well as the role of the US and the increasing presence of China in those processes. Finally, the connections and interactions between the regional processes in Latin America and the Asia-Pacific are analyzed and compared.