This chapter analyses the principles and characteristics of Chilean foreign trade policy. Firstly, Chile embraces a policy of multilateralism that aims to participate in a high number of organizations and treaties. Secondly, the participation of Chile in international organizations is defined by rational and strategic considerations, with authorities looking to get access to the benefits of participation but rejecting a loss of sovereignty. Finally, trade issues dominate Chilean foreign policy over political matters. The chapter examines and provides an historical explanation of these principles. This is complemented by statistical data. Finally, a comparative description of Chilean relations with its main trade partners is made.