ABSTRACT

In contrast to allergic contact dermatitis (ACD), irritant contact dermatitis (ICD) is the result of unspecified damage attributable to contact with chemical substances that cause an inflammatory reaction of the skin [1]. The clinical appearance of ICD is extremely variable. It is determined by the type of irritant and a dose-effect relationship [2]. The clinical morphology of acute irritant contact dermatitis as one side of the spectrum is characterized by erythema, edema, vesicles that may coalesce, bullae, and oozing. Necrosis and ulceration can be seen with corrosive materials. Clinical appearance of chronic ICD is dominated by redness, lichenification, excoriations, scaling, and hyperkeratosis.