ABSTRACT

Many published accounts of the composition of lipids from human stratum corneum have been complicated by the almost inevitable presence of sebaceous lipids as well as exogenous contaminants. When stratum corneum samples are obtained from excised skin, there is almost always massive contamination with subcutaneous triglycerides as well as fatty acids derived from the subcutaneous fat. In addition, precautions must be taken to avoid contamination with environmental contaminants such as alkanes and cosmetic components. As a result of these complications, much work has been done with pig skin as a model [1-6].