ABSTRACT

Adsorption of amino acids, peptides, and nucleic acid constituents on silica surfaces is a very important aspect of biomolecular adsorption. One cannot imagine the modem practice of their analysis and separation, so widely used in biotechnology, medicine, diagnostics, etc., without high-performance liquid chromatographic (HPLC) methods employing silica stationary phases (see, for example, Refs. 1-3). The rational design of new biocompatible materials and drug delivery systems also needs a detailed knowledge on biomolecule adsorption interactions. Furthermore, studying the adsorption of the biopolymers' building blocks and the development of structureproperty relationships can give insight to the interfacial behavior of the biopolymers themselves.