ABSTRACT
Rapid developments in our understanding of neurobiological mechanisms of neuronal plasticity and recovery after injury, coupled with advances in behavioral theory and methodology for physiotherapeutic interventions, are now resulting in a fundamental change in treatment approach to neurological disorders. New intervention strategies are beginning to be based not only upon empirical clinical trial evidence, but also upon evidence-based neuroscientific models of plasticity and repair mechanisms, derived from animal and human studies. This recent change in approach is thought to be so integral to current thinking, and so rapid, that some have referred to an impending new paradigm shift in neurorehabilitation (1,2).
