ABSTRACT

While the basic principles with regard to identification and management of fungal infections in immunocompromised children are similar to those encountered in adult patients, there are additional considerations for pediatric patients at risk for fungal infections. Notably, the developmental immaturity of host responses to infection encountered during the first few months of life, place young infants at particularly high risk for a wide range of infectious complications, especially with fungal pathogens (1). Both term and preterm infants may be viewed as immunocompromised hosts and are at high risk for neonatal fungal infections, especially with candidiasis (2-6). However, the consequences are particularly severe in very low birth weight infants (7).