ABSTRACT

Herpes simplex viruses (HSV) infect amajority of the world population. Traditionally, the causative viral subtypes have been associated with different anatomical sites of infection. HSV-1 is usually associated with non-sexually acquired orolabial and extragenital conditions commonly encountered in childhood, while HSV-2 is generally viewed as the cause of sexually acquired genital infections seen in adults. This distinction is no longer valid because an increasing number of genital infections are now caused by HSV-1 (1).