ABSTRACT
Immunosuppressed patients are at increased risk of developing infections because of immune system impairment. Infections caused by viruses are of particular concern in patients in whom the defect of immunity involves the cytotoxic T cells, i.e., the cells primarily involved in immune defense against viruses. A deficit of T-cell-mediated immunity is encountered in a number of conditions dominated by immune suppression, including transplanted and oncology patients, as well as patients with other congenital or acquired immune deficiencies.
