ABSTRACT
Diabetic nephropathy is a chronic complication that develops in approximately one-third of all patients with diabetes. Clinical studies have found a link between a number of clinical or laboratory features and the risk of developing diabetic nephropathy. It is important to detect the factors since some of them are remediable and can direct preventive interventions. Diabetic complications are often designed as microvascular and macro-vascular in nature, since they are caused by alterations of small or medium or large arterial vessels of vital organs such as the retina, peripheral nerves, heart, brain, aorta, arteries of the limbs. The optimal range of blood pressure in patients with type 2 diabetes is unclear. In the Hypertension Optimal Treatment Trial involving patients with type 2 diabetes, there were no more cardiovascular events when diastolic blood pressure was 70–84 mmHg than when it was 85 mmHg or higher.
