ABSTRACT
Sarcoidosis is an immunomediated multisystem disorder of unknown
cause(s) frequently presenting with hilar lymphadenopathy, pulmonary infil-
tration, and ocular and skin lesions (1). The liver, spleen, lymph nodes, sali-
vary glands, heart, nervous system, muscles, and bones are other frequently involved organs. From an immunological point of view, impaired delayed
type hypersensitivity, imbalance of CD4/CD8T-cell subsets, an influx of
Th1 helper cells to sites of activity, hyperactivity of B-cells, and circulation
of immune complexes represent the most relevant features.
