ABSTRACT

Bone function is multifaceted, including serving as levers to facilitate muscle-controlled movements, protection of vital organs, storehouse of minerals, and production of hematopoietic cells. These factors are synergistically interrelated and, on a larger scale, may represent mutually antagonistic objectives. For instance, bones have to be strong enough to withstand forces generated during daily activities but, at the same time, should minimize their mass as maintaining bone tissue is metabolically very costly.