ABSTRACT

The risk of death from liver disease is 2.5-fold higher among patients with type 2 diabetes mellitus compared to the general population (1). The most common liver disease among diabetics is non-alcoholic liver disease (NAFLD), which refers to the presence of hepatic steatosis not associated with excessive ethanol consumption. NAFLD occurs as a histological and clinical spectrum of disease; “simple steatosis” has a relatively benign course that rarely leads to advanced liver disease, whereas steatosis plus inflammation and/or fibrosis (non-alcoholic steatohepatitis or NASH) has the potential to lead to cirrhosis.