ABSTRACT
The introduction of relatively large volumes of sample into a capillary gas chromatography (GC) column has been studied for some time. The analysis of complex matrices, such as those encountered in environmental, medical, agricultural, fossil fuel and biotechnology areas has become a very important area of separation science, motivating advances in theory and technique to the point where modern high resolution chromatography operates at levels which are close to the theoretical limits. The various reconcentration mechanisms which have been postulated to accomplish large injections into a capillary GC can be divided into different categories. The solvent effect mechanism postulated for the introduction of large volumes of solvent into a capillary GC requires that said introduction be made at temperatures the boiling point of the solvent, and in addition, the solvents used must wet the uncoated inlet.
