ABSTRACT

Removal of glass particles to obtain clean surfaces has been the objective of a gamut of manufacturers ranging from those producing pharmaceutical devices to those producing electron devices. This chapter reviews the different techniques to remove glass particles from surfaces and critically assesses each of these techniques. Effects of parameters such as particle size and humidity on removal efficiencies are also discussed. Chemical Methods are very appropriate if extremely small particles exist and the cleanliness requirements are very stringent. For pharmaceutical applications where contamination is considered in terms of parts per billion, this technique is preferred and often used. Chemical attack methods could be classified as either leaching or etching. Glass particles can be removed by using centrifugal forces. For cleanliness requirements of parts per billion, chemical methods are the best. Mechanical methods are good, but it should be noted that as the particle size decreases, higher scrubbing force is required for removal of particles.